Prenatal Infection and Schizophrenia: A Review of Epidemiologic and Translational Studies

Prenatal Infection and Schizophrenia: A Review of Epidemiologic and Translational Studies, American Journal of Psychiatry 2010; 167:261-280 Alan S. Brown, M.D., M.P.H., and Elena J. Derkits, B.A. Abstract: An emerging literature from epidemiologic, clinical, and preclinical investigations has provided evidence that gestational exposure to infection contributes to the etiology of schizophrenia. In recent years, these studies [...]

Psychiatrists’ Role in the Health of the Pregnant Mother and the Risk for Schizophrenia in Her Offspring

Psychiatrists’ Role in the Health of the Pregnant Mother and the Risk for Schizophrenia in Her Offspring, American Journal of Psychiatry 167:239-240, March 2010 Robert Freedman, M.D. Editorial Abstract: The review article by Brown and Derkits in this issue (1) is one of a series of papers that have been published in The American Journal of Psychiatry [...]

Bipolar disorder is highly comorbid with substance use disorders – STEP-BD

Impact of Substance Use Disorders on Recovery From Episodes of Depression in Bipolar Disorder Patients: Prospective Data From the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), American  Journal of Psychiatry 2010 167: 289-297 Michael J. Ostacher,  et al. Abstract: Bipolar disorder is highly comorbid with substance use disorders, and this comorbidity may be associated with [...]

Combining Antidepressant Medications: A Good Idea?

Combining Antidepressant Medications: A Good Idea? American  Journal of Psychiatry, March 1, 2010; 167(3): 241 – 243 A J Rush Abstract: In this issue, Blier and colleagues report on an important 6-week double-blind randomized trial in outpatients with nonpsychotic major depressive disorder (1). Mirtazapine combined with venlafaxine, bupropion, or fluoxetine resulted in significantly greater sustained remission rates (58%, [...]

Combination of antidepressant medications from treatment initiation for major depressive disorder: a double-blind randomized study

Combination of antidepressant medications from treatment initiation for major depressive disorder: a double-blind randomized study , American  Journal of  Psychiatry 2010; 167:281-288 Pierre Blier, M.D., Ph.D., Herbert E. Ward, M.D., Philippe Tremblay, M.D., Louise Laberge, M.D., Chantal Hébert, R.N., and Richard Bergeron, M.D., Ph.D Abstract: Objective: Various classes of antidepressant medications generally induce remission of [...]